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Catalog #
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Source:
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Lot #
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Size:
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AT3851a
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mouse
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0.1mg
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Type:
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Accession:
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Clone Name:
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Isotype:
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Mab
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NP_000014
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3C4
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IgG2b Kappa
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Applications:
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Reactivity:
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MW:
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ELISA,WB-Re,WB-Tr
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H
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42875 Da
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Target/Specificity:
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SGCA (NP_000014, 26 a.a. ~ 134 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Other Names:
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50-DAG, A2, ADL, DAG2, DMDA2, LGMD2D, SCARMD1, adhalin
sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
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Application Data:
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Western Blot analysis of SGCA expression in transfected 293T cell line by SGCA monoclonal antibody (M01), clone 3C4.
Lane 1: SGCA transfected lysate(42.9 KDa).
Lane 2: Non-transfected lysate.
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Background:
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This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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Background References:
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Product Citations:
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Application Notes:
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| ELISA | 1ug/ml~3ng/ml |
| Western blot | 1:500~1000 |
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Format:
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Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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Storage:
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For continuous use, store at 2-8°C for one-two days. For extended storage, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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