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Catalog #
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Source:
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Lot #
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Size:
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AT4033a
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mouse
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09324
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0.1mg
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Type:
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Accession:
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Clone Name:
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Isotype:
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Mab
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AAH03139
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2C11
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IgG2a kappa
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Applications:
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Reactivity:
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MW:
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ELISA,IF,S-ELISA,WB-Re
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H
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47687 Da
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Target/Specificity:
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SQSTM1 (AAH03139, 1 a.a. ~ 441 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Other Names:
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PDB3, ZIP3, p60, p62sequestosome 1
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Application Data:
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Immunofluorescence of monoclonal antibody to SQSTM1 (AT4033a) on HeLa cell . [antibody concentration 10 ug/ml] |
Detection limit for recombinant GST tagged SQSTM1 is approximately 0.03ng/ml as a capture antibody. |
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Background:
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This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]
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Background References:
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Product Citations:
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Application Notes:
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| ELISA | 1ug/ml~3ng/ml |
| Western blot | 1:500~1000 |
| Immunofluorescence | |
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Format:
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Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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Storage:
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For continuous use, store at 2-8°C for one-two days. For extended storage, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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