SUMOplot Analysis Program

Sumoylation Antibodies

Abgent has the most extensive panel of sumoylation antibodies. This includes

SUMO Isoforms
SUMO ligases
SUMO proteases
SUMO conjugating enzymes
SUMO site-specific proteins

The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. The presence of this post-translational modification may help explain larger MWs than expected on SDS gels due to attachment of SUMO protein (11kDa) at multiple positions in your protein.

SUMO-1 (small ubiquitin-related modifier; also known as PIC1, UBL1, Sentrin, GMP1, and Smt3) is a member of the ubiquitin and ubiquitin-like superfamily. Most SUMO-modified proteins contain the tetrapeptide motif B-K-x-D/E where B is a hydrophobic residue, K is the lysine conjugated to SUMO, x is any amino acid (aa), D or E is an acidic residue.

The SUMOplot™ Analysis Program predicts the probability for the SUMO consensus sequence (SUMO-CS) to be engaged in SUMO attachment. The SUMOplot™ score system is based on two criteria:

direct amino acid match to SUMO-CS.
substitution of the consensus amino acid residues with amino acid residues exhibiting similar hydrophobicity.

Update: SUMOplot is currently undergoing maintenance and will be available by February 1st. Please check back periodically as the program may be available before that date. Thank you for your understanding and we are quickly working to get this valuable resource back up as soon as possible.