SUMOplot™ Analysis Program

Sumoylation Antibodies

Abgent has the most extensive panel of sumoylation antibodies. This includes

SUMO Isoforms
SUMO ligases
SUMO proteases
SUMO conjugating enzymes
SUMO site-specific proteins

The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. The presence of this post-translational modification may help explain larger MWs than expected on SDS gels due to attachment of SUMO protein (11kDa) at multiple positions in your protein.

SUMO-1 (small ubiquitin-related modifier; also known as PIC1, UBL1, Sentrin, GMP1, and Smt3) is a member of the ubiquitin and ubiquitin-like superfamily. Most SUMO-modified proteins contain the tetrapeptide motif B-K-x-D/E where B is a hydrophobic residue, K is the lysine conjugated to SUMO, x is any amino acid (aa), D or E is an acidic residue.

The SUMOplot™ Analysis Program predicts the probability for the SUMO consensus sequence (SUMO-CS) to be engaged in SUMO attachment. The SUMOplot™ score system is based on two criteria:

direct amino acid match to SUMO-CS.
substitution of the consensus amino acid residues with amino acid residues exhibiting similar hydrophobicity.

Identify Protein Sequence:

Enter one protein ID (SwissProt, PIR, GenPept, or RefSeq)

-- OR --
Enter Sequence (Number and Space will be deleted)