|Application ||WB, IHC-F|
|Calculated MW||45385 Da|
|Purification||Antisera to DR3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.|
|Immunogen||Peptide from extracellular domain of human DR3.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tumor necrosis factor receptor superfamily member 25, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, Death receptor 3, Lymphocyte-associated receptor of death, LARD, Protein WSL, Protein WSL-1, TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1|
|Target/Specificity||Rabbit anti-Human DR3 recognizes death receptor 3. DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas/CD95 (Chinnaiyan, A. et al.1996). The receptor for DR3 has very recently been identified and has been termed Apo-3L (Marsters, S. et al.1998). DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, a functionally induces apoptosis and NF-KB activation.|
|Preservative & Stabilisers||0.02% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human DR3 (Ed) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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