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>   home   >   Products   >   Primary Antibodies   >   Anti-Human Mcm5 Antibody, clone CRCT5.1    

Anti-Human Mcm5 Antibody, clone CRCT5.1

Mouse Anti-Human Monoclonal Antibody

  • IHC - Anti-Human Mcm5 Antibody, clone CRCT5.1  ABD10126
    Staining of formalin fixed, paraffin embedded human tonsil with Mouse anti Humann MCM5
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P33992
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names CRCT5.1
Calculated MW 82286 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Bacterially expressed human Mcm5.
Shelf Life 18 months from date of despatch.
Gene ID 4174
Other Names DNA replication licensing factor MCM5,, CDC46 homolog, P1-CDC46, MCM5, CDC46
Target/Specificity Mouse anti-Human Mcm5 antibody, clone CRCT5.1 recognizes human Mcm-5 (minichromosome maintenance protein 5), also known as DNA replication licensing factor MCM5 or P1-CDC46. Mcm5 is a nuclear protein of ~95kDa with an important role in the control of DNA replication (Snyderet al.2005).It has been reported that immunocytochemical assessment of Mcm5 expression may be of value in improving the accuracy of cervical smear testing for the detection of malignancy (Murphyet al.2004).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Mcm5 Antibody, clone CRCT5.1 is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Dart, D.A. et al. (2004) Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase.
J Biol Chem. 279: 16433-40. 2. Adams, K.E. et al. (2006) Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex.
Oncogene. 25: 3894–904. 3. Gakiopoulou, H. et al. (2007) Minichromosome maintenance proteins 2 and 5 in non-benign epithelial ovarian tumours: relationship with cell cycle regulators and prognostic implications.
British Journal of Cancer 97: 1124–34. 4. Guida, T. et al. (2005) Mitogenic effects of the up-regulation of minichromosome maintenance proteins in anaplastic thyroid carcinoma.
J Clin Endocrinol Metab. 90: 4703-9. 5. Polo, S.E. et al. (2010) Clinical significance and prognostic value of chromatin assembly factor-1 overexpression in human solid tumours.
Histopathology. 57: 716-24.1. Williams, G.H. et al. (1998) Improved cervical smear assessment using antibodies against proteins that regulate DNA replication.
Proc. Natl. Acad. Sci. USA. 14932-14937.

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Cat# ABD10126
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