|Application ||FC, IP, Hagg|
|Calculated MW||82824 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Other Names||Kell blood group glycoprotein, 3.4.24.-, CD238, KEL|
|Target/Specificity||Mouse anti-Human CD238 antibody, clone BRIC203 recognizes human CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on the ~93 kDa erythrocyte membrane glycoprotein.In hemagglutination tests, Mouse anti-Human CD238 antibody, clone BRIC203 reacts with Kp (a-b+) but not Kp (a+b-). In addition Mouse anti-Human CD238 antibody, clone BRIC203 will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but not react with Ko erythrocytes. Weaker staining in flow cytometry is observed on erythroblasts derived from CD34+ hematopoietic progenitor cells, compared to Kp (a-b+) red blood cells.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD238 Antibody, clone BRIC203 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Parsons, S.F. et al. (1993) Monoclonal antibodies against Kell glycoprotein: serology, immunochemistry and quantification of antigen sites.Transfus Med. 3 (2): 137-42. 2. Van Der Schoot. et al. (2002) CD238 - Kell.Leucocyte Typing VII pp 584-5. 3. Miyazak, T. et al. (2002) Serological analyses of anti-kell monoclonal antibodies using MAIEA assay.Leucocyte Typing VII pp 585-8.
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