|Application ||WB, FC|
|Calculated MW||34481 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Recombinant human NKp46 extracellular Ig-like domain (amino acids 22-255).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, NKp46, hNKp46, CD335, NCR1, LY94|
|Target/Specificity||Mouse anti-Human CD335 antibody, clone N1d9 recognizes the human natural cytotoxicity receptor CD335, also known as NKp46. NKp46 is expressed on circulating NK cells and is reported to be a novel NK-specific cell surface molecule that is involved in human NK cell activation.Natural killer (NK) cells contribute to the innate immune response by directly lysing a variety of tumor cells and cells that are infected by viruses. Natural cytotoxicity receptors (NCR) are a family of Ig-like activation receptors that are reported to play an important role in tumor cell recognition. Three NCR have been reported to-date, which include NKp46, NKp30 and NKp44. The ligands for these NCR have not been identified.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD335 Antibody, clone N1d9 is for research use only and not for use in diagnostic or therapeutic procedures.|
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