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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Mouse CD279 Antibody, clone RMP1-30    

Anti-Mouse CD279 Antibody, clone RMP1-30

Rat Anti-Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q02242
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2b
Clone Names RMP1-30
Calculated MW 31842 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen PD-1 transferred BHK cells.
Shelf Life 18 months from date of despatch.
Gene ID 18566
Other Names Programmed cell death protein 1, Protein PD-1, mPD-1, CD279, Pdcd1, Pd1
Target/Specificity Rat anti-Mouse CD279 antibody, clone RMP1-30 recognizes mouse CD279, a ~55 kDa cell surface protein, a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279. Rat anti-Mouse CD279 antibody, clone RMP1-30 does not block the binding of either B7-H1-Ig or B7-DC-Ig fusion proteins to PD-1 transfected BHK cells.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse CD279 Antibody, clone RMP1-30 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Matsumoto, K. et al. (2004) B7-DC regulates asthmatic response by an IFN-gamma-dependent mechanism.
J Immunol. 172 (4): 2530-41. 2. Bartkowiak, T. (2013) Novel Imaging-Based Techniques Reveal a Role for PD-1/PD-L1 in Tumor Immune Surveillance in the Lung.
UT GSBS Dissertations and Theses (Open Access). Paper 354. 3. Hu, Z. et al. (2013) Regulatory CD8+ T cells associated with erosion of immune surveillance in persistent virus infection suppress in vitro and have a reversible proliferative defect.
J Immunol. 191 (1): 312-22.

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Cat# ABD10171
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