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Rabbit Anti-Bacterial Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E, IP |
|---|---|
| Primary Accession | P01556 |
| Reactivity | Bacteria |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Polyclonal IgG |
| Immunogen | Purified choleragenoid |
|---|---|
| Shelf Life | 18 months from the date of despatch. |
| Other Names | Cholera enterotoxin subunit B, Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, ctxB, toxB |
| Target/Specificity | Rabbit anti-cholera toxin beta antibody recognizes the beta subunit of cholera toxin.The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. |
| Preservative & Stabilisers | 0.09% Sodium Azide (NaN3) |
| Storage | Store at +4℃ or at -20 ℃. |
| Precautions | Anti-Cholera Toxin beta Antibody (FITC) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
1. Thangawng, A.L. et al. (2010) A hard microflow cytometer using groove-generated sheath flow for multiplexed bead and cell assays.Anal Bioanal Chem. 398: 1871-81. 2. Becker, P.M. et al. (2010) Inhibition of binding of the AB5-type enterotoxins LT-I and cholera toxin to ganglioside GM1 by galactose-rich dietary components.Foodborne Pathog Dis. 7: 225-33.
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