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Anti-hCG beta (Free Specific) Antibody, clone P1G7F12 (BIO-BCG-005)

Mouse Anti-Human Monoclonal Antibody

Product Information
Primary Accession P01233
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names P1G7F12 (BIO-BCG-005)
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen Human Chorionic Gonadotropin beta subunit from human pregnancy urine
Shelf Life 18 months from date of despatch.
Other Names Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta, CGB, CGB3
Target/Specificity Mouse anti-hCG beta (free specific) antibody, clone P1G7F12 (BIO-BCG-005) recognizes the beta subunit of human chorionic gonadotropin (hCG).Minimal cross-reactivity (0.5%) has been observed with the intact hCG molecule and negligible reactivity has been shown with the human luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH). Human chorionic gonadotropin exists in 5 different variants (hCG, sulfated hCG, hyperglycosylated hCG, free beta hCG and hyperglycosylated free beta) that share the same amino acid sequence but have different functions (Cole 2012). hCG is a glycoprotein of 237 amino acids. Regular hCG has a molecular weight of ~36kDa where oligosaccharides account for 25-30% of the MW (Cole 2010). hCG is composed of a 92-amino acid alpha subunit, common to the LH, FSH and TSH hormones, and of a unique beta subunit, which is recognized by Mouse anti-hCG beta antibody, clone P1G7F12.Production of progesterone is not the only role of hCG: it also has numerous other functions, during pregnancy and as a marker for certain cancers (Cole 2012), (Cole 2010) and (Cole 2009).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-hCG beta (Free Specific) Antibody, clone P1G7F12 (BIO-BCG-005) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Cole, L.A. (2009) Human chorionic gonadotropin tests.
Expert Rev Mol Diagn. 9:721-472. Cole, L.A. (2010) Biological functions of hCG and hCG-related molecules.
Reprod Biol Endocrinol. 8:102-115.3. Cole, L.A. (2012) hCG, the wonder of today's science.
Reprod Biol Endocrinol. 10:24-41

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Cat# ABD10403
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