|Purification||Antisera to cortisol were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to the amino acids 1 - 3 of the native molecule conjugated to Bovine Serum Albumin.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||ABD10440 detects cortisol, a glucocorticoid that is produced by the adrenal cortex in response to pituitary adrenocorticotropic hormone (ACTH) stimulation. Cortisol is secreted into the plasma whereby the majority is bound to corticosteroid binding globulin (CBG) and serum albumin. Cortisol is up-regulated in response to stress, and leads to an increase in blood pressure and blood sugar, and an immunosuppressive action to help restore body homeostasis. Cortisol also has multiple effects on human behaviour, including sleep patterns, mood, and the reception of sensory input. Changes in cortisol expression have pathological consequences; hypercortisolism results in Cushing's syndrome, whilst hypocortisolism leads to Addison's disease.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Cortisol Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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