|Calculated MW||85698 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Synthetic peptide corresponding to the amino acids 729 - 742 of the native molecule conjugated to Keyhole limpet Haemocyanin.Peptide sequence: FVGWFLGWDDDYWS|
|Shelf Life||18 months from date of despatch.|
|Other Names||Gelsolin, AGEL, Actin-depolymerizing factor, ADF, Brevin, GSN|
|Target/Specificity||ABD10528 is specifc for human gelsolin and reacts with both the plasma and cytoplasmic forms.Gelsolin is a calcium and polyphosphoinositide regulated actin-binding protein which consists of 6 homologous domains. It is involved in cell morphology, motility, growth and apoptosis through its ability to affect filament assembly by severing actin filaments, forming a nucleus for polymerisation, and capping the fast exchanging end of the filaments.It exists as an intracellular form, found in the cytoplasm and mitochondria, and an extracellular form located in blood plasma.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Gelsolin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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