|Clone Names||5F9 (BGN/6E10)|
|Calculated MW||304790 Da|
|Immunogen||Purified native human thyroglobulin.|
|Other Names||Thyroglobulin, Tg, TG|
|Target/Specificity||Mouse anti-Human Thyroglobulin antibody, clone 5F9 recognizes human thyroglobulin (Tg). Thyroglobulin is a 2768 amino acid ~670kDa homodimeric protein containing multiple thyroglobulin type 1 domains. Thyroglobulin is produced by the thyroid gland and is a precursor in the production of the thyroid hormones Triiodothyronine (T3) and Thyroxine (T4), important for regulating metabolic processes in the body (Uniprot: P01266).Mutations in the thyroglobulin gene can lead to developmental and autoimmune diseases including Thyroid dyshormonogenesis 3 (Targovniket al.2010) and Autoimmune thyroid disease 3 (Banet al.2003).Mouse anti-Human Thyroglobulin antibody, clone 5F9 has been used successfully as a capture reagent in a sensitive sandwich ELISA for the detection of thyroglobulin in human serum and plasma samples.|
|Precautions||Anti-Human Thyroglobulin Antibody, clone 5F9 (BGN/6E10) is for research use only and not for use in diagnostic or therapeutic procedures.|
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