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Goat Anti-Mouse Polyclonal Antibody
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Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P70658 |
| Reactivity | Mouse |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | Polyclonal IgG |
| Calculated MW | 40426 Da |
| Other Species | X |
|---|---|
| Purification | Antiserum to mouse CD184 / CXCR4 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. |
| Immunogen | Synthetic peptide YSEEVGSGDYDSNKEPCFRDENVHFNR corresponding to amino acids 14-40 within the N-terminal region of mouse CD184 / CXCR4. |
| Shelf Life | 18 months from date of despatch. |
| Gene ID | 12767 |
| Other Names | C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Fusin, Leukocyte-derived seven transmembrane domain receptor, LESTR, Pre-B-cell-derived chemokine receptor, PB-CKR, Stromal cell-derived factor 1 receptor, SDF-1 receptor, CD184, Cxcr4, Cmkar4, Lestr, Sdf1r |
| Target/Specificity | Goat anti-Mouse CD184 / CXCR4 recognises an epitope within the N-terminal (NT) region of mouse CD184, otherwise known as CXCR4 (C-X-C chemokine receptor type 4), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, ubiquitously expressed in blood and tissue cells, which acts as a specific receptor for the chemokine SDF-1 (Stromal cell-derived factor 1).Interaction of CD184 with SDF-1 mediates the chemotaxis of progenitor and mature blood cells, and is critical for B-lymphopoiesis and myelopoiesis. CD184 is a major co-receptor for infection by T-cell tropic strains of HIV1, and also a primary receptor for some HIV2 isolates.This antibody is reported as being suitable for use in immunocytochemistry on mouse spleen leucocytes. |
| Preservative & Stabilisers | 0.1% Sodium Azide (NaN3); 0.1% Bovine Serum Albumin; |
| Storage | Store at -20℃ only. |
| Precautions | Anti-Mouse CD184 / CXCR4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Research Areas
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Cat# ABD10851
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