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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Cadherin 13 Antibody    

Anti-Human Cadherin 13 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-Human Cadherin 13 Antibody  ABD10877
    Western blot analysis of whole cell lysates from NIH-3T3 mouse embryonic fibroblasts probed with Rabbit anti Human cadherin 13 at 0.5(A) and 1(B) ug/ml
  • IF - Anti-Human Cadherin 13 Antibody  ABD10877
    Immunofluorescence staining of K562 human erythromyeloblastoid cells with Rabbit anti Human cadherin 13
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P55290
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 78287 Da
Additional Information
Other Species M
Purification Antisera to Cadherin 13 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen Synthetic peptide corresponding to N-terminus of human Cadherin 13.
Shelf Life 18 months from date of despatch.
Gene ID 1012
Other Names Cadherin-13, Heart cadherin, H-cadherin, P105, Truncated cadherin, T-cad, T-cadherin, CDH13, CDHH
Target/Specificity Rabbit anti-Human cadherin 13 antibody recognizes human Cadherin 13, a ~78 kDa, calcium-dependent, glycoprotein. While Cadherin 13 is a member of the cadherin family, it lacks their conserved cytoplasmic region, being instead anchored to the plasma membrane via glycosylphosphatidylinositol linkage. It is expressed in the heart and CNS with the exception of the cerebellum and spinal cord.Cadherin 13 is classified as a cell-cell adhesion molecule, although it is likely that it’s role is in signalling and not physical adhesion. It is involved in regulating low-density lipoprotein-initiated cell proliferation, keratinocyte proliferation, neural cell growth and may play a role in metabolic regulation. Cadherin 13 protects endothelial cells from oxidative stress-induced apoptosis and may contribute to progression of vascular disorders such as atherosclerosis, restenosis and tumour angiogenesis.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Cadherin 13 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Ivanov, D. (2004) T-cadherin upregulation correlates with cell-cycle progression and promotes proliferation of vascular cells.
Cardiovasc Res. 64:132-143.

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Cat# ABD10877
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