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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Protein Kinase C zeta (N-Terminal) Antibody    

Anti-Human Protein Kinase C zeta (N-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human Protein Kinase C zeta (N-Terminal) Antibody  ABD10912
    Staining of formalin fixed, paraffin embedded human cerebellum with Rabbit anti Human protein kinase c zeta
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q05513
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 67660 Da
Additional Information
Purification Antisera to protein kinase C zeta were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide: near the N-terminus of human protein kinase C zeta.
Shelf Life 18 months from date of despatch.
Gene ID 5590
Other Names Protein kinase C zeta type,, nPKC-zeta, PRKCZ, PKC2
Target/Specificity Rabbit anti-human protein kinase c zeta polyclonal antibody recognizes PKCζ a serine/threonine kinase involved in a variety of cell processes including differentiation and proliferation. PKCζ activation is involved in the mitogen-activated protein kinase cascade, transcriptional factor NFkB activation, ribosomal S6-protein kinase signalling, and cell polarity. Work by al. in mice has indicated that inhibition of expression of PHGDH by PKCζ acts at a tumor supressor and that loss of PKCζ allows tumor cells to proliferate under glucose deprived conditions leading to poor prognosis.Rabbit anti-human protein kinase c zeta detects an epitope within the N-terminal (NT) region of PKCζ. PKCζ is a member of the atypical PKC subfamily. PKCζ may also be a potential therapeutic target in asthma, and a putative role in other pulmonary diseases, including chronic obstructive pulmonary disease (COPD).
Preservative & Stabilisers 0.1% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Protein Kinase C zeta (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Hirai, T. and Chida, K. (2003) Protein kinase C zeta (PKC zeta): Activation mechanisms and cellular functions.
J. Biochem. 133: 1-7.

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Cat# ABD10912
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