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Anti-Human SLC5A11 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human SLC5A11 Antibody  ABD10930
    Staining of formalin fixed, paraffin embedded human brain cortex with Rabbit anti Human SLC5A11
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WWX8
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 74036 Da
Additional Information
Purification Antisera to SLC5A11 were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide: Extracellular domain of human SLC5A11, conjugated to KLH.
Shelf Life 18 months from date of despatch.
Gene ID 115584
Other Names Sodium/myo-inositol cotransporter 2, Na(+)/myo-inositol cotransporter 2, Sodium-dependent glucose cotransporter, Sodium/glucose cotransporter KST1, Sodium/myo-inositol transporter 2, SMIT2, Solute carrier family 5 member 11, SLC5A11 {ECO:0000312|EMBL:EAW55781.1}
Target/Specificity ABD10930 detects an epitope within the extracellular domain of human SLC5A11, a 75kD Na+/myo-inositol cotransporter also known as SMIT2. SLC5A11 can also cotransport D-glucose and D-xylose, and the myo-inositol (MI) epimer D-chiro-inositol.MI is the most biologically abundant cyclic polyol, which function as precursors to molecules involved in cell signalling, cell adhesion and vesicular trafficking. MI also controls intracellular osmolarity by serving as a compatible osmolyte, which allows renal cells to function under hypertonic conditions. SLC5A11 is mainly expressed in the kidney, and particularly in the kidney cortex, where it is reported to be responsible for the apical transport of MI into the proximal tubule. It is also highly expressed in the heart, skeletal muscle, liver and placenta.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human SLC5A11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Coady, M.J. et al. (2002) Identification of a novel Na+/myo-inositol cotransporter.
J. Biol. Chem. 277: 35219-35224.2. Roll, P. et al. (2002) New human sodium/glucose cotransporter gene (KST1): identification, characterization, and mutation analysis in ICCA (infantile convulsions and choreoathetosis) and BFIC (benign familial infantile convulsions) families.
Gene. 285: 141-148.

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Cat# ABD10930
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