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Anti-Caspase-14 (C-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-Caspase-14 (C-Terminal) Antibody  ABD10938
    Western blot analysis of whole cell lysate from Jurkat cells probed with Rabbit anti caspase-14 either in the absence (A) or presence (B) of blocking peptide
  • IHC - Anti-Caspase-14 (C-Terminal) Antibody  ABD10938
    Immunohistochemical staining of human liver with Rabbit anti caspase-14
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P31944
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 27680 Da
Additional Information
Other Species Rat,M
Purification Antisera to Caspase-14 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen A 16 amino acid peptide from near the carboxy-terminus of human Caspase-14.
Shelf Life 18 months from date of despatch.
Gene ID 23581
Other Names Caspase-14, CASP-14, 3.4.22.-, Caspase-14 subunit p19, Caspase-14 subunit p10, CASP14
Target/Specificity ABD10938 detects an epitope within the C-terminal (CT) region of human caspase-14; a 27kD cysteine protease which is activated by zymogen processing during cellular differentiation. It is highly expressed by keratinocytes and trophoblast cells of the placenta, with lower expression in the choroid plexus, the pigmented layer of the retina, and hair follicles. Expression of the caspase-14 gene has recently been identified in epithelial tumours, including cervical and bladder carcinoma. The biological function of caspase-14 in tumour and normal tissue remains to be classified.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Caspase-14 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Park, K. et al. (2006) Expression and characterization of constitutively active human caspase-14.
Biochem. Biophys. Res. Commun. 347: 941-948.2. Koenig U. et al. (2005) Aberrant expression of caspase-14 in epithelial tumors.
Biochem Biophys Res Commun. 335: 309-313.3. White, L. et al. (2007) Caspase-14: a new player in cytotrophoblast differentiation.
Reprod. Biomed. Online. 14: 300-307.

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Cat# ABD10938
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