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Anti-Human CTRP5 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-Human CTRP5 Antibody  ABD10939
    Western blot analysis of whole cell lysate from Caco-2 epithelial colorectal adenocarcinoma cells probed with Rabbit anti Human CTPR5 at 1(A), 2(B) and 4(C) ug/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BXJ0
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 25298 Da
Additional Information
Purification Antisera to human CTRP5 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen A 15 amino acid peptide from near the centre of human CTRP5.
Shelf Life 18 months from date of despatch.
Gene ID 114902
Other Names Complement C1q tumor necrosis factor-related protein 5, C1QTNF5, CTRP5
Target/Specificity ABD10939 detects an epitope within C1q and TNF related protein 5 (CTRP5), also known as C1QTNF5. CTRP5 encodes a novel short chain collagen which is widely expressed with highest expression in the retinal pigment epithelium (RPE) and ciliary epithelium (CE). It is a secretory protein, which associates with membrane type frizzled related protein (MFRP), and may aid the adhesion of basal RPE to Bruch membrane.Mutation to CTRP5 causes it to be retained in the endoplasmic reticulum, and can lead to late-onset retinal degeneration (LORD) and long anterior lens zonules. CTRPs are often highly modified post-translationally, so whereas the predicted molecular weight for CTRP5 is 25kD, ABD10939 detects a single band at 40kD.
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CTRP5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Shu, X. et al. (2006) Disease mechanisms in late-onset retinal macular degeneration associated with mutation in C1QTNF5.
Hum. Mol. Genet. 15: 1680-1689.2. Ayyagari, R. et al. (2005) Late-onset macular degeneration and long anterior lens zonules result from a CTRP5 gene mutation.
Invest. Ophthalmol. Vis. Sci. 46: 3363-3371.

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Cat# ABD10939
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