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>   home   >   Products   >   Primary Antibodies   >   Anti-GSK3 beta (pSer9) Antibody    

Anti-GSK3 beta (pSer9) Antibody

Rabbit Anti-Rat Polyclonal Antibody

  • WB - Anti-GSK3 beta (pSer9) Antibody  ABD10957
    Western blot of rat cortex lysate showing phosphospecific immunolabeling of the ~46 kDa GSK3β protein phosphorylated at Ser9
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P18266
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 46742 Da
Additional Information
Purification Antisera to rat GSK3 beta (pSer9) were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Phosphopeptide corresponding to amino acid sequence surrounding phoshorylated seine 9 of rat GSK3 beta.
Shelf Life 12 months from date of reconstitution.
Gene ID 84027
Other Names Glycogen synthase kinase-3 beta, GSK-3 beta,, Factor A, FA, Serine/threonine-protein kinase GSK3B,, Gsk3b
Target/Specificity ABD10957 recognises glycogen synthase 3 (GSK3) beta phosphorylated at serine 9. This is a 46 kDa member of the serine/threonine protein kinase family. Two isforms of GSK3 exist, alpha and beta. GSK3 beta is expressed in the testis, thymus, prostate, and ovary as well as being expressed at low levels in lung, brain and kidney tissue.GSK3 beta is involved in many signalling pathways including energy metabolism, body pattern formation and microtubule growth and stability (which aids axon growth). GSK3 beta is also thought to be involved in oncogenesis and the hormonal control of several regulatory proteins including glycogen synthase.Phosphorylation of serine-9 inhibits GSK3 beta function.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 50% Glycerol; 0.01% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-GSK3 beta (pSer9) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Green, J. (2004) Lkb1 and GSK3-beta: kinases at the center and poles of the action
Cell Cycle 3:12-14. 2. Papkoff, J. et al. (1998) WNT-1 and HGF regulate GSK3 beta activity and beta-catenin signaling in mammary epithelial cells.
Biochem. Biophys. Res. Commun. 247:851-8. 3. Stambolic, V. et al. (1994) Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation.
Biochem, J. 303:701-4. 4. Garrido, J. et al. (2007) GSK3 alpha and GSK3 beta are necessary for axon formation.
FEBS Lett. 581:1579-86.

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Cat# ABD10957
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