|Calculated MW||20576 Da|
|Purification||Antiserum to human ATF3 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide sequence corresponding to amino acid sequence 113-130 of human ATF3.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, ATF3|
|Target/Specificity||ABD11030 recognizes human Activating Transcription factor 3 (ATF3), a 20.6 kDa member of the activation transcription factor (ATF)/cCAMP responsive element-binding (CREB) family of transcription factors. Two isoforms of ATF3 have been identified. Isoform 1, the longer of the two, represses transcription from promoters with ATF binding elements by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2, which lacks the leucine zipper protein-dimerization motif, stimulates transcription, by sequestering inhibitory cofactors away from the promoters. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes .|
|Preservative & Stabilisers||0.01% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human ATF3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.
Request Quote Here