|Application ||WB, IHC-P, E|
|Calculated MW||77960 Da|
|Purification||Antiserum to human ATG7 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide sequence corresponding to amino acid sequence 558-569 of Human ATG7 protein.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Ubiquitin-like modifier-activating enzyme ATG7, ATG12-activating enzyme E1 ATG7, Autophagy-related protein 7, APG7-like, hAGP7, Ubiquitin-activating enzyme E1-like protein, ATG7, APG7L|
|Target/Specificity||ABD11031 recognises human Autophagy-related protein 7, known also as Ubitiquin Activating Enzyme-E1 like Protein, ATG7 and APG7, a 78kDa cytoplasmic protein. In mammalian cells, ATG7 is essential for autophagy conjugation systems, autophagosome formation, starvation-induced bulk degradation of proteins and organelles. Studies indicate that caspase-8 may alter APG7 levels and thus the APG7 program of autophagic cell death. ATG7 is evolutionally conserved and exhibits high homology within mammalian species. It expressed in wide range of tissues including kidney, live, bone marrow and lymph nodes.|
|Preservative & Stabilisers||0.01% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human ATG7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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