|Other Accession||P20337, O95716, P20336|
|Calculated MW||25952 Da|
|Purification||Antisera to Rab3 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.|
|Immunogen||Peptide corresponding to amino acid residues from the N-terminal region of rat Rab3 conjugated to keyhole limpet hemocyanin (KLH).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Ras-related protein Rab-3C, RAB3C|
|Target/Specificity||ABD11074 recognises Rab3, a group of closely related GTP-binding proteins (Rab3A, Rab3B, Rab3C and Rab3D) involved in regulating membrane traffic. Rab3 proteins are expressed in high levels in the brain and endocrine tissues but are also found elsewhere. They are localised on exocytic vesicles and in the brain they cycle on and off synaptic vesicles in parallel with the release of neurotransmitters. Many functions have been proposed for the Rab3 proteins, from fusion to docking and the biogenesis of vesicles. They are thought to play an important role in presynaptic vesicle trafficking and priming.|
|Preservative & Stabilisers||0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Rat RAB3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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