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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human Hsc70 Antibody    

Anti-Human Hsc70 Antibody

Goat Anti-Human Polyclonal Antibody

  • WB - Anti-Human Hsc70 Antibody  ABD11080
    Western blot analysis of Hsc70 expression in A431 cell line lysate using Goat anti Human Hsc70 antibody followed by HRP conjugated anti goat IgG. Detection by chemiluminescence
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11142
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 70898 Da
Additional Information
Purification Antiserum to human Hsc70 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen Peptide sequence C-EKLQGKINDEDKQK corresponding to the internal region of Hsc70 (NP_006588.1)
Shelf Life 18 months from date of despatch.
Gene ID 3312
Other Names Heat shock cognate 71 kDa protein, Heat shock 70 kDa protein 8, Lipopolysaccharide-associated protein 1, LAP-1, LPS-associated protein 1, HSPA8, HSC70, HSP73, HSPA10
Target/Specificity Goat anti-Human Hsc70 antibody recognizes human Heat shock cognate 71 kDa protein, also known as Heat shock 70 kDa protein 8 or Lipopolysaccharide-associated protein 1. Hsc70 is a 646 amino acid ubiquitously expressed cytoplasmic heat-shock cognate protein and member of the heat shock protein 70 family, encoded for by the HSPA8 gene. Goat anti-Human Hsc70 antibody recognizes epitopes in the region between amino acids 555 and 570 of Hsc70 isoform 1, missing in isoform 2.Heat shock proteins are a group of constitutively expressed or heat/stress-inducible proteins which act as molecular chaperones and play an essential role in protein folding/unfolding and transport of proteins across membranes. Hsc70 facilitates the correct folding of newly-synthesized polypeptides (Flynnet al.1989) and also participates in the ATPase disassociation of clathrin-coated vesicles during endocytosis, in conjunction with the co-chaperone auxilin (Jianget al.1997).
Preservative & Stabilisers 0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Hsc70 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Schmid, S.L. (1997) Clathrin-coated vesicle formation and protein sorting: An integrated process.
Annu. Rev. Biochem. 66: 511-548.

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Cat# ABD11080
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