|Application ||WB, IHC-P|
|Calculated MW||55760 Da|
|Purification||Antiserum to human TEM7 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||A peptide corresponding to a 16 amino acid sequence from near the center of human TEM7.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Plexin domain-containing protein 1, Tumor endothelial marker 3, Tumor endothelial marker 7, PLXDC1, TEM3, TEM7|
|Target/Specificity||ABD11101 recognises human Tumour endothelial marker 7 (TEM7), a 55.8 kDa protein belonging to the plexin family. TEM7 is strongly expressed in endothelial cells from colorectal cancer and from primary cancers of the lung, liver, brain, breast and pancreas. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma. Studies have indicated the existence of least four isoforms of TEM7 which include membrane bound, secreted and intracellular forms. TEM7 is not detectable in endothelial cells from normal tissues.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-TEM7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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