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Anti-Human Cerebellin-1 (C-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-Human Cerebellin-1 (C-Terminal) Antibody  ABD11105
    Western Blot analysis of HEK293 human epithelial kidney cells probed with Rabbit anti Human precerebellin at 2(A) and 4(B) ug/ml
  • ICC - Anti-Human Cerebellin-1 (C-Terminal) Antibody  ABD11105
    Immunocytochemical staining of NIH-3T3 mouse embryonic fibroblasts with Rabbit anti precerebellin
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23435
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 21097 Da
Additional Information
Other Species M,Rat
Purification Antiserum to human Precerebellin was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen A peptide corresponding to an 16 amino acid sequence from near the carboxy terminus of human Precerebellin.
Shelf Life 18 months from date of despatch.
Gene ID 869
Other Names Cerebellin-1, Precerebellin, Cerebellin, CER, [des-Ser1]-cerebellin, CBLN1
Target/Specificity ABD11105 recognises human Precerebellin also known as Cerebellin-1, CBLN1 or Cerebellin precursor, a secreted membrane protein with a predicted molecular weight of 21kDa.Precerebellin is required for synapse integrity and synaptic plasticity and for the ER export and secretion of CBLN3. Precerebellin exerts neuromodulatory functions including directly stimulating norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. Research indicates that Precerebellin may also be involved in a wider range of functions than have been so far demonstrated.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Cerebellin-1 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Albertin G., et al (2000) Cerebellin stimulates the secretory activity of the rat adrenal gland: in vitro and in vivo studies.
Neuropeptides 34:7-112. Mazzocchi G., et al (1999) Cerebellin enhances in vitro secretory activity of human adrenal gland.
J. Clin. Endocrinol. Metab. 84:632-5.3. Urade Y., et al (1991) Precerebellin is a cerebellum-specific protein with similarity to the globular component C1q B chain.
PNAS 88:1069-73

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Cat# ABD11105
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