|Application ||WB, IHC-P|
|Calculated MW||28585 Da|
|Purification||Antiserum to PHAP I (CT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by immunoaffinity chromatography.|
|Immunogen||A peptide corresponding to amino acids at the carboxy terminus of human PHAP I.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Acidic leucine-rich nuclear phosphoprotein 32 family member A, Acidic nuclear phosphoprotein pp32, pp32, Leucine-rich acidic nuclear protein, LANP, Mapmodulin, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A, Putative HLA-DR-associated protein I, PHAPI, ANP32A, C15orf1, LANP, MAPM, PHAP1|
|Target/Specificity||Rabbit anti-PHAP I (C-Terminal) antibody recognizes the carboxy Terminal of human Acidic leucine-rich nuclear phosphoprotein 32 family member A, also known as putative LHA-DR-associated protein, PHAP I, Acidic nuclear phosphoprotein pp32, Leucine-rich acidic nuclear protein, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A or Mapmodulin. PHAP I is a249 amino acid member of the ANP32 family , containing 4 leucine rich repeats and a single LRRCT domain.. PHAP I plays a role in a number of cellular processes, including proliferation, differentiation, apoptosis and tumour suppression. PHAp- 1 is involved in the activation of caspase-9 following apatosome formation (Chianget al.2003). PHAP 1 is ubiquitously expressed with principally nuclear expression.Rabbit anti-PHAP I (C-Terminal) antibody does not cross-react with other isoforms of PHAP.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-PHAP I (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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