|Application ||WB, IHC-P|
|Calculated MW||43884 Da|
|Purification||Antiserum to human AdipoR2 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide CSRTPEPDIRLRKGHQLDGTRRGDNDSHQG corresponding to amino acids 11-40 within the N-terminal region of human AdipoR2.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Adiponectin receptor protein 2, Progestin and adipoQ receptor family member II, ADIPOR2, PAQR2|
|Target/Specificity||Goat anti-Human AdipoR2 antibody recognizes an epitope within the N-terminal (NT) region of Adiponectin Receptor protein 2 (AdipoR2), a transmembrane protein and member of the ADIPOR family, expressed mainly in the liver and skeletal muscle, which acts a receptor for both globular and full-length adiponectin. AdipoR2 acts as a mediator of fatty acid oxidation, glucose uptake by adiponectin and increased AMPK, PPARalpha ligand activity, thereby playing an important role in the regulation of glucose and lipid metabolism, and in oxidative stress.Goat anti-Human AdipoR2 is reported as suitable for use in immunocytochemistry on acetone fixed cells.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3); 0.1% Bovine Serum Albumin;|
|Storage||Store at -20℃ only.|
|Precautions||Anti-Human Adipor2 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Shen, X. et al. (2012) Pioglitazone prevents hyperglycemia induced decrease of AdipoR1 and AdipoR2 in coronary arteries and coronary VSMCs.Mol Cell Endocrinol. 363 (1-2): 27-35.
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