|Application ||WB, E|
|Calculated MW||37337 Da|
|Purification||Antiserum to human Mcl-1 (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide sequence C-AGVGAGLAYLIR from the C-Terminal region of Mcl-1 (NP_068779.1).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl2-L-3, Bcl-2-related protein EAT/mcl1, mcl1/EAT, MCL1, BCL2L3|
|Target/Specificity||Goat anti-Human Mcl-1 antibody recognises an epitope within the C-Terminal (CT) region of human Mcl-1, otherwise known as Myeloid cell leukaemia sequence 1, a mitochondrial-associated anti-apoptotic member of the Bcl-2 family, which acts as both an enhancer of cell survival (isoform 1), and promoter of cell death (isoform 2).Mcl-1 is expressed in many different cell lines, and several types of cancer, and blockage of its function, may prove to be a useful therapeutic agent in the treatment of malignancies and inflammatory and infectious diseases.Goat anti-Human Mcl-1 antibody is expected to recognise the longer gene product, isoform 1.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin;|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Mcl-1 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Cencic, R. et al. (2013) Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A.Blood Cancer J. 3: e128.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.
Request Quote Here