|Application ||WB, IHC-P|
|Calculated MW||31368 Da|
|Purification||Antisera to human XPA were raised by repeated immunisation of rabbits with highly purified antigen.|
|Immunogen||Recombinant human XPA|
|Shelf Life||18 months from date of despatch.|
|Other Names||DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing protein, XPA, XPAC|
|Target/Specificity||ABD11316 recognises the human DNA repair associated protein designated XPA (Xeroderma pigmentosum A).XPA is a zinc finger protein of 31kD, although it demonstrates an electophoretic mobility of 40-42kD doubled. XPA is involved in the nucleotide excision repair process.ABD11316 recognises both normal and recombinant XPA, and shows no cross reactivity with other XP proteins.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human XPA Antibody (Serum) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Jones, C.J. and Wood, R.D. (1993) Preferential binding of the Xeroderma pigmentosum group A complementing protein to damaged DNA.Biochemistry 32: 12096-12101. 2. Li, R-Y. et al. (1998) Interactions of the Transcription/DNA repair factor TFIIH and XP repair proteins with DNA lesions in a cell-free repair assay.J. Mol. Biol. 281: 211-218. 3. Araújo SJ (2001) Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome.Mol Cell Biol. 21: 2281-91.
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