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Anti-Human GRO beta Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human GRO beta Antibody  ABD11422
    Formalin fixed, paraffin embedded human colorectal adenocarcinoma stained with Rabbit anti Human GRO-β following heat mediated antigen retrieval with sodium citrate buffer (pH6.0)
  • IHC-P - Anti-Human GRO beta Antibody  ABD11422
    Formalin fixed, paraffin embedded human colorectal adenocarcinoma stained with Rabbit anti Human GRO-β following heat mediated antigen retrieval with sodium citrate buffer (pH6.0)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, Func
Primary Accession P19875
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 11389 Da
Additional Information
Purification Antisera to human GRO-beta were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Recombinant human GRO-beta.
Shelf Life 12 months from date of reconstitution.
Gene ID 2920
Other Names C-X-C motif chemokine 2, Growth-regulated protein beta, Gro-beta, Macrophage inflammatory protein 2-alpha, MIP2-alpha, GRO-beta(5-73), GRO-beta-T, Hematopoietic synergistic factor, HSF, SB-251353, CXCL2, GRO2, GROB, MIP2A, SCYB2
Target/Specificity Rabbit anti-Human GRO beta antibody recognizes human GRO-beta, also known as Growth-regulated protein beta, C-X-C motif chemokine 2, Macrophage inflammatory protein 2-alpha, MIP-2α or CXCL2. GRO beta is a ~7.9 kDa CXC chemokine and one of three closely related, but distinct GRO gene products, which act as chemoattractants and activators of neutrophils and basophils.Like GRO-alpha (CXCL1) and GRO-gamma (CXCL3), GRO-beta contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors, though studies have shown that GRO-beta has a lower potency and receptor binding affinity (Geiseret al.1993).
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human GRO beta Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Haskill, S. et al. (1990) Identification of three related human GRO genes encoding cytokine functions.
Proc Natl Acad Sci U S A. 87 (19): 7732-6. 2. Geiser, T. et al. (1993) The Interleukin-8-related chemotactic cytokines GROalpha, GRObeta, and GROgamma activate human neutrophil and basophil leukocytes.
J. Biol. Chem. 268: 15419-15424. 3. Kogan-Sakin, I. et al. (2009) Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1.
Carcinogenesis 30: 698-705.

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Cat# ABD11422
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