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Anti-Human GRO gamma Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human GRO gamma Antibody  ABD11423
    Staining of formalin fixed, paraffin embedded human colo-rectal adenocarcinoma with Rabbit anti Human GRO gamma
  • IHC-P - Anti-Human GRO gamma Antibody  ABD11423
    Staining of formalin fixed, paraffin embedded human colo-rectal adenocarcinoma with Rabbit anti Human GRO gamma
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, Func
Primary Accession P19876
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 11342 Da
Additional Information
Purification Antisera to human GRO-gamma were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Recombinant human GRO-gamma (PHP117)
Shelf Life 12 months from date of reconstitution.
Gene ID 2921
Other Names C-X-C motif chemokine 3, GRO-gamma(1-73), Growth-regulated protein gamma, GRO-gamma, Macrophage inflammatory protein 2-beta, MIP2-beta, GRO-gamma(5-73), CXCL3, GRO3, GROG, SCYB3
Target/Specificity Rabbit anti-Human GRO gamma antibody recognizes human GRO-gamma, also known as CXCL3, Growth-regulated protein gamma, GRO-gamma(1-73), Macrophage inflammatory protein 2-beta or MIP2-beta. GRO gamma is a ~7.9kDa CXC chemokine and one of three closely related, but distinct GRO gene products, which act as chemoattractants and activators of neutrophils and basophils.Like GRO-alpha (CXCL1) and GRO-beta (CXCL2), GRO-gamma contains the ELR-motif (N-Terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors, though studies have shown a difference in the potency and receptor binding affinity of these three proteins (Wuytset al.1999).
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human GRO gamma Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Kogan-Sakin, I. et al. (2009) Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1.
Carcinogenesis 30: 698-705.1. Haskill, S. et al. (1990) Identification of three related human GRO genes encoding cytokine functions.
Proc Natl Acad Sci U S A. 87 (19): 7732-6.2. Geiser, T. et al. (1993) The Interleukin-8-related chemotactic cytokines GROalpha, GRObeta, and GROgamma activate human neutrophil and basophil leukocytes.
J. Biol. Chem. 268: 15419-15424.

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Cat# ABD11423
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