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Anti-Human MIP-3 alpha Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human MIP-3 alpha Antibody  ABD11427
    Formalin fixed, paraffin embedded colorectal adenocarcinoma stained with Rabbit anti Human MIP-3α following heat mediated antigen retrieval using sodium citrate buffer (pH6.0)
  • IHC-P - Anti-Human MIP-3 alpha Antibody  ABD11427
    Formalin fixed, paraffin embedded colorectal adenocarcinoma stained with Rabbit anti Human MIP-3α following heat mediated antigen retrieval using sodium citrate buffer (pH6.0)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, Func
Primary Accession P78556
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 10762 Da
Additional Information
Purification Antisera to human MIP-3 alpha were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Recombinant human MIP-3 alpha.
Shelf Life 12 months from date of reconstitution.
Gene ID 6364
Other Names C-C motif chemokine 20, Beta-chemokine exodus-1, CC chemokine LARC, Liver and activation-regulated chemokine, Macrophage inflammatory protein 3 alpha, MIP-3-alpha, Small-inducible cytokine A20, CCL20(1-67), CCL20(1-64), CCL20(2-70), CCL20, LARC, MIP3A, SCYA20
Target/Specificity Rabbit anti-Human MIP-3 alpha antibody recognizes human MIP-3 alpha, (Macrophage Inflammatory Protein 3 alpha), otherwise known as CCL20, a 70 amino acid CC chemokine predominantly expressed by the liver, lymph nodes, appendix, spleen and pancreas and also by the thymus, small intestine, foetal lungs and PBLs.MIP-3 alpha acts as a chemoattractant for memory T lymphocytes, immature dendritic cells and B lymphocytes, being the only CC chemokine known to bind to the G-protein linked 7-transmembrane receptor CCR6. Further properties of MIP-3 alpha include antimicrobial activity, inhibition of the in vitro proliferation of bone marrow immature myeloid progenitors and the stimulation of the growth and migration of pancreatic carcinoma cells.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human MIP-3 alpha Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Hieshima, K. et al. (1997) Molecular cloning of a novel human CC chemokine liver and activation-regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2.
J. Biol. Chem. 272: 5846-5853.2. Schutyser, E. et al. (2003) The CC chemokine CCL20 and its receptor CCR6.
Cytokine Growth Factor Rev. 14: 409-426.3. Kleeff, J. et al. (1999) Detection and localization of Mip-3alpha/LARC/Exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer.
Int. J. Cancer. 81: 650-657.

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Cat# ABD11427
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