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Anti-Synapsin I (pSer603) Antibody

Rabbit Anti-Rat Polyclonal Antibody

  • WB - Anti-Synapsin I (pSer603) Antibody  ABD11480
    Western blot of rat cortex lysate showing phosphospecific immunolabeling of ~78 kDa synapsin 1 protein phosphorylated at Ser603
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P09951
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 73988 Da
Additional Information
Purification Antisera to phosphorylated synapsin I were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic phosphopeptide corresponding to an amino acid sequence within Synapsin I which includes the phosphorylated residue Ser603.
Shelf Life 12 months from date of reconstitution.
Gene ID 24949
Other Names Synapsin-1, Synapsin I, Syn1
Target/Specificity Rabbit anti-phosphorylated Synapsin I antibody recognizes rat Synapsin I, when phosphorylated at serine 603.Synapsin I is a neuron-specific phosphoprotein which is associated with synaptic vesicles in the central and peripheral nervous system and is involved in the regulation of synaptic vesicle availablility and thought to play a key role in brain plasticity.Synapsin I is phosphorylated at serine 603 by CaMKII.
Preservative & Stabilisers 0.09% Sodium Azide; 0.01% Bovine Serum Albumin; 50% Glycerol
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Synapsin I (pSer603) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Jovanovic, J.N. et al. (2001) Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+ - dependent glutamate release in isolated nerve terminals.
J. Neurosci. 21: 7944 - 7953. 2. Kao, H.T. et al. (2002) A protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth.
Nature Neurosci. 5: 431 - 437. 3. Menegon, A. et al. (2000) Use of phosphosynapsin I-specific antibodies for image analysis of signal transduction in single nerve terminals.
J. Cell Sci. 113: 3573 - 3582.

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Cat# ABD11480
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