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Rabbit Anti-Human Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P98170 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Polyclonal IgG |
| Calculated MW | 56685 Da |
| Other Species | M |
|---|---|
| Purification | Antisera to human XIAP were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. |
| Immunogen | Synthetic peptide corresponding to a thirteen amino acid sequence with the C-terminal region of human XIAP. |
| Shelf Life | 18 months from date of despatch. |
| Gene ID | 331 |
| Other Names | E3 ubiquitin-protein ligase XIAP, 6.3.2.-, Baculoviral IAP repeat-containing protein 4, IAP-like protein, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3, X-linked inhibitor of apoptosis protein, X-linked IAP, XIAP, API3, BIRC4, IAP3 |
| Target/Specificity | ABD11500 is specific for human X-chromosome linked inhibitor of apoptosis (XIAP). XIAP is an endogenous inhibitor of cell death, which functions by suppressing caspases 3, 7, and 9. The protein is also reported to play a a role in the activation of NF kappa B and the regulation of cyclins and cyclin-dependent kinase inhibitors (CDKIs). Regulators of XIAP activity include XAF-1 and Smac. ABD11500 detects a band of approximately 57KDa in human kidney lysates. |
| Preservative & Stabilisers | 0.02% Sodium Azide |
| Storage | Store at +4℃ or at -20 ℃. |
| Precautions | Anti-XIAP (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Research Areas
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Cat# ABD11500
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