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Anti-Chicken Interleukin-6 Antibody

Rabbit Anti-Chicken Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E, Func
Primary Accession Q90YI0
Reactivity Chicken
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 26790 Da
Additional Information
Purification Antisera to chicken Interleukin 6 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography on protein G.
Immunogen Recombinant chicken IL-6(PAP003)
Shelf Life 18 months from date of despatch.
Gene ID 395337
Other Names Interleukin-6, ChIL-6, IL-6, IL6
Target/Specificity ABD11503 recognizes chicken Interleukin 6 (chIL-6).Mammalian IL-6 is a multifunctional pro-inflammatory cytokine, which plays a major role in the regulation of immune responses, haematopoiesis and the induction of acute phase responses. The action of IL-6 occurs via the signal transducing receptor chain gp130 and the IL-6 receptor alpha chain is responsible for ligand binding. IL-6 is produced by a wide variety of cells including B lymphocytes, T lymphocytes, monocytes/macrophages, fibroblasts and endothelial cells and has a widespread cellular effect, including B and T lymphocytes, hepatocytes and cells of the CNS. Studies relating to the properties of chIL-6 have been limited, but demonstrate that hepatocyte-stimulating factor (HSF), secreted by lipopolysaccharide (LPS)-stimulated macrophages, induces fibronectin production in cultured chicken hepatocytes, and that HSF produced by LPS-treated fibroblasts, was neutralized by an antiserum to recombinant HuIL-6 (rHuIL-6). rHuIL-6 has also been shown as biologically active on chicken hepatocytes. ABD11503 neutralizes chicken IL-6 in 7D1 bioassays.
Preservative & Stabilisers Preservative Free
Storage Store at -20℃ only.
PrecautionsAnti-Chicken Interleukin-6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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5. De Boever, S. et al. (2010) Flow cytometric differentiation of avian leukocytes and analysis of their intracellular cytokine expression.
Avian Pathol. 39: 41-6.1. Staeheli, P. et al. (2001) Cytokines of Birds: Conserved functions – A largely different look.
J. Interferon and Cytokine Research 21: 993-1010.2. Schneider, K. et al. (2001) Chicken interleukin-6. cDNA structure and biological properties.
Eur. J. Biochem. 268: 4200-4206.3. Amrani, D.L. et al. (1986) Effect of hepatocyte-stimulating factor and glucocorticoids on plasma fibronectin levels.
Biochem. J. 238(2): 365-371.4. Samad, F. et al. (1993) Stimulation of chick hepatocyte fibronectin production by fibroblast-conditioned medium is due to interleukin 6.
Biochim. Biophys. Acta. 1181(3): 207-213.

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Cat# ABD11503
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