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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Chicken Interferon beta Antibody    

Anti-Chicken Interferon beta Antibody

Rabbit Anti-Chicken Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IP, Func
Primary Accession Q90873
Reactivity Chicken
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 23686 Da
Additional Information
Purification Antisera to chicken Interferon Beta were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography on protein G.
Immunogen Recombinant chicken Interferon Beta.
Shelf Life 18 months from date of despatch.
Gene ID 554219
Other Names Interferon type B, IFN-beta, IFNB, IFN2
Target/Specificity Rabbit anti-Chicken Interferon beta antibody recognizes chicken Interferon beta (chIFN-beta). Reports suggest that chIFN exhibits properties similar to mammalian IFN type I (IFNI).Functional studies revealed the presence of two distantly related IFNI genes, designated as IFN alpha and IFN beta, found on chicken chromosome Z. The serological distinction between these two IFNs has been verified using neutralisation assays, and there is evidence that the antiviral activity of chIFN-beta is approximately ten-fold less compared to chIFN-alpha. This would suggest that chIFNbeta might have a different physiological role, though chIFN-beta is expressed strongly in virus-infected cells. Rabbit anti-Chicken Interferon beta antibody (ABD11505) does not cross react with IFN gamma.This antiserum neutralizes chIFN-beta and can be used to discriminate IFN alpha and IFN beta bioactivities, (Schwarz, al.).
Preservative & Stabilisers Preservative Free
Storage Store at -20℃ only.
PrecautionsAnti-Chicken Interferon beta Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Schwarz, al. (2004) Synthesis of IFN-beta by virus-infected chicken embryo cells demonstrated with specific antisera and a new bioassay.
J. Interferon Cytokine Res. 24: 179-184.1. Staeheli, P. et al. (2001) Cytokines of Birds: Conserved functions – A largely different look.
J. Interferon Cytokine Res. 21: 993-1010.2. Sick, C. et al. (1996) A family of genes coding for two serologically distinct chicken interferons
J. Biol. Chem. 271: 7635-7639.

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Cat# ABD11505
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