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>   home   >   Products   >   Primary Antibodies   >   Anti-Sheep CD41/CD61 Antibody, clone CO.35E4    

Anti-Sheep CD41/CD61 Antibody, clone CO.35E4

Mouse Anti-Sheep Monoclonal Antibody

  • FC - Anti-Sheep CD41/CD61 Antibody, clone CO.35E4  ABD11540
    Staining of sheep peripheral blood platelets with Mouse anti Sheep CD4/CD61
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Sheep
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names CO.35E4
Additional Information
Other Species Ga,Cat,Rb,Dog,Hs,B
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Immunogen Sheep leucocytes
Shelf Life 18 months from date of despatch.
Target/Specificity Mouse anti-Sheep CD41/CD61 antibody, clone CO.35E4 recognizes ruminant CD41/CD61, also known as GpIIb/IIIa. CD41/CD61 is a calcium-complex dependent heterodimer and is expressed almost exclusively on platelets and on their precursors, the megakaryocytes. This complex is an activation-dependent receptor for RGD (Arg-Gly-Asp)-containing glycoproteins such as fibrinogen, fibronectin, von Willebrand factor, thrombospondin and vitronectin. It plays a central role in platelet aggregation and haemostasis.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Sheep CD41/CD61 Antibody, clone CO.35E4 is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Brodersen, R. et al. (1998) Analysis of the immunological cross reactivities of 213 well characterized monoclonal antibodies with specificities against various leucocyte surface antigens of human and 11 animal species:
Vet. Immunol. Immunopathol. 64: 1-13. 2. Pintado, C. O. et al. (1995) Characterisation of a membrane receptor on ruminants and equine platelets and peripheral blood leucocytes similar to the human integrin receptor glycoprotein IIb/IIIa (CD41/CD61).
Vet Immunol. Immunopathol. 44 (3-4): 359 - 368. 3. Lalko, C. et al. (2003) Equine platelet CD62P (P-selectin) expression: a phenotypic and morphologic study.
Vet. Immunol. Immunopathol. 91: 119 - 134. 4. Major, T.C. et al. (2010) The attenuation of platelet and monocyte activation in a rabbit model of extracorporeal circulation by a nitric oxide releasing polymer.
Biomaterials. 31: 2736-45. 5. Brainard, B.M. et al. (2012) Treatment with aspirin or clopidogrel does not affect equine platelet expression of P selectin or platelet-neutrophil aggregates.
Vet Immunol Immunopathol. 149: 119-25.

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Cat# ABD11540
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