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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Rat CD45R Antibody, clone HIS24 (6B6)    

Anti-Rat CD45R Antibody, clone HIS24 (6B6)

Mouse Anti-Rat Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04157
Reactivity Rat
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names HIS24 (6B6)
Calculated MW 143269 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Single cell suspension of rat peyers patches.
Shelf Life 18 months from date of despatch.
Gene ID 24699
Other Names Receptor-type tyrosine-protein phosphatase C,, Leukocyte common antigen, L-CA, T200, CD45, Ptprc
Target/Specificity Mouse anti-Rat CD45R antibody, clone HIS24 recognizes the high molecular weight form of the leucocyte common antigen (LCA) or CD45. CD45R is expressed on mature and precursor B lymphocytes, and to some extent on marginal zone B cells and a small subset of T cells.Mouse anti-Rat CD45R antibody, clone HIS24 is routinely used as a pan-B-cell marker for immunohistochemical studies on brain tissue (Aliet al.2005), pancreas (Homo-Delarcheet al.2006), pulmonary tissue (Foxwellet al.2001) and in flow cytometry on bone marrow cells (Prakapaset al.1993).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Rat CD45R Antibody, clone HIS24 (6B6) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Kroese, F.G. et al. (1987) B lymphocyte differentiation in the rat: production and characterization of monoclonal antibodies to B lineage-associated antigens.
Eur J Immunol. 1987 Jul;17(7):921-8. 2. Ali, S. et al. (2005) Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model.
Cancer Res. 65: 7194-204. 3. Homo-Delarche, F. et al. (2006) Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat.
Diabetes. 2006 Jun;55(6):1625-33. 4. Ma, H. et al. (2007) Features of chronic allograft rejection on rat small intestine transplantation. Pediatr Transplant.
Pediatr Transplantation 11:165-72. 5. Prakapas, Z. et al. (1993) Enrichment and characterization of thymus-repopulating cells in stroma-dependent cultures of rat bone marrow.
J Cell Sci. 104: 1039-48. 6. Erben, R.G. et al. (1998) Ovariectomy augments B lymphopoiesis and generation of monocyte-macrophage precursors in rat bone marrow.
Am J Physiol. 274: E476-83. 7. Horibe, E.K. et al. (2008) Rapamycin-conditioned, alloantigen-pulsed dendritic cells promote indefinite survival of vascularized skin allografts in association with T regulatory cell expansion.
Transpl Immunol. 18: 307-18. 8. Ménoret, S. et al. (2013) Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases.
FASEB J. 27: 703-11. 9. Saiki, T. et al. (2001) In vivo roles of donor and host dendritic cells in allogeneic immune response: cluster formation with host proliferating T cells.
J Leukoc Biol. 69: 705-12. 10. Foxwell, A.R. et al. (2001) CD8+ T cells have an essential role in pulmonary clearance of nontypeable Haemophilus influenzae following mucosal immunization.
Infect Immun. 69: 2636-42. 11. Shen, J. et al. (1998) Histological characterization and pharmacological control of chronic rejection in xenogeneic and allogeneic heart transplantation.
Transplantation. 1998 Sep 27;66(6):692-8.

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Cat# ABD11568
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