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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Anti-Human Acetylcholine Receptor beta Antibody, clone B3    

Anti-Human Acetylcholine Receptor beta Antibody, clone B3

Mouse Anti-Human Monoclonal Antibody

  • WB - Anti-Human Acetylcholine Receptor beta Antibody, clone B3  ABD11569
    A lysate overexpressing acteylcholine receptor beta probed with Mouse anti Human acetylcholine receptor beta followed by Rabbit F(ab')2 anti Mouse IgG:HRP
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11230
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names B3
Calculated MW 56698 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Human Acetylcholine Receptor (AChR).
Shelf Life 18 months from date of despatch.
Gene ID 1140
Other Names Acetylcholine receptor subunit beta, CHRNB1, ACHRB, CHRNB
Target/Specificity Mouse anti-Human Acetylcholine Receptor beta antibody, clone B3 exhibits homogenous, high avidity binding to the beta subunit of nicotinc AChR, an integral membrane and cholinergic receptor, consisting of four further subunits: alpha, delta, gamma (immature muscle) and epsilon (mature muscle). The binding of the neurotransmitter acetylcholine to AChR, results in conformational change affecting all subunits, and initiates the opening of an ion-conducting channel across the plasma membrane of certain neurons, and neuromuscular junctions.Mouse anti-Human Acetylcholine Receptor beta antibody, clone B3 has been shown to bind to recombinant AChR beta in Western blotting
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Acetylcholine Receptor beta Antibody, clone B3 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Whiting, P.J. et al. (1986) Monoclonal Antibodies that distinguish between normal and denervated human acetylcholine receptor.
J. Neuroimmunol. 11: 223-235. 2. Roberts, A. et al. (1992) Search for cross reactive idiotypes on monoclonal and myasthenia gravis acetylcholine receptor antibodies.
Autoimmunity 21: 53-60. 3. Heidenreich F. et al. (1988) Differences in fine specificity of anti-acetylcholine receptor antibodies between subgroups of spontaneous myasthenia gravis of recent onset and of penicillamine induced myasthenia.
Autoimmunity 2: 31-37. 4. Whiting, P. et al. (1986) Myasthenia gravis: Monoclonal anti-human acetylcholine receptor antibodies used to analyse antibody specificities and responses to treatment.
Neurology 36: 612-617. 5. Schluep, M. et al. (1987) Acetylcholine receptors in human thymic myoid cells in situ: An immunohistological study.
Annals of Neurology 22: 212-222.

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Cat# ABD11569
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