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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Mouse Interleukin-2 Antibody, clone JES6-1A12    

Anti-Mouse Interleukin-2 Antibody, clone JES6-1A12

Rat Anti-Mouse Monoclonal Antibody

  • WB - Anti-Mouse Interleukin-2 Antibody, clone JES6-1A12  ABD11586
    Western blot analysis of mouse IL-2 recombinant protein probed with Rat anti Mouse Interleukin-2 followed by F(ab')2 Rabbit anti Rat IgG:HRP
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04351
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names JES6-1A12
Calculated MW 19400 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography from tissue culture supernatant
Immunogen E. coli expressed recombinant mouse IL-2
Shelf Life 18 months from date of despatch.
Gene ID 16183
Other Names Interleukin-2, IL-2, T-cell growth factor, TCGF, Il2, Il-2
Target/Specificity Rat anti-mouse IL-2, clone JES6-1A12recognizesmouse Interleukin-2. IL-2 is a cytokine required for T-cell proliferation.Rat anti-mouse IL-2, clone JES6-1A12 is reported to have neutralizing activity for IL-2 (Abramset al.1992) and Bihlet al.2010).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse Interleukin-2 Antibody, clone JES6-1A12 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Abrams, J.S. et al. (1992) Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10and IL-5 in clinical samples.
Immunol. Rev. 127: 5-24. 2. Sander, B. et al. (1993) Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining.
J. Immunol. Methods 166: 201-214. 3. Rigby S. et al. (2003) Total lymphoid irradiation nonmyeloablative preconditioning enriches for IL-4 producing CD4+ - TNK cells and skews differentiation of immunocompetent donor CD4+ cells.
Blood 101:2024-2032. 4. Eyles J. et al. (2002) Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1.
J. Biol Chem 277:43735-43740. 5. Kitching A. et al. (2000) IL-18 has IL-12-independent effects in delayed-type hypersensitivity : studies in cell-mediated crescentic glomerulonephritis.
J. Immunol. 165:4649-4657. 6. Bihl, F. et al. (2010) Primed antigen-specific CD4+ T cells are required for NK cell activation in vivo upon Leishmania major infection.
J Immunol. 185: 2174-81 7. Tachibana, M. et al. (2000) Coreceptor function of mutant human CD4 molecules without affinity to gp120 of human immunodeficiency virus.
J Biol Chem. 275: 20288-94.

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Cat# ABD11586
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