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>   home   >   Products   >   Primary Antibodies   >   Anti-Bovine CD1w3 Antibody, clone CC43    

Anti-Bovine CD1w3 Antibody, clone CC43

Mouse Anti-Bovine Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Bovine
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names CC43
Additional Information
Other Species Ga,Sh
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Shelf Life 18 months from date of despatch.
Target/Specificity Mouse anti-Bovine CD1w3 antibody, clone CC43 recognises the bovine CD1w3 cell surface antigen, a ~44kDa molecule expressed as a heterodimer with beta 2 microglobulin.Bovine CD1w3 is expressed by immature cortical thymocytes but not by mature CD2+ or WC1+ cells in peripheral lymphoid tissues. It is also expressed by B cells, monocytes and subsets of dendritic cells. refinement of the binding specificity of Mouse anti-Bovine CD1w3 antibody, clone CC43 indicates that the antibody binds to the bovine CD1d molecule (Nguyen 2011). Bovine Cd1d binds short chain glycosphingolipids (Wanget al.2012).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Bovine CD1w3 Antibody, clone CC43 is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Howard, C.J. et al. (1993) A new bovine leukocyte antigen cluster comprising two monoclonal antibodies, CC43 and CC118, possibly related to CD1.
Vet Immunol Immunopathol. 39: 69-76. 2. Naessens, J. et al. (1993) Cross-reactivity of workshop antibodies with cells from domestic and wild ruminants.
Vet Immunol Immunopathol. 39 (1-3): 283-90. 3. Naessens, J. et al. (1997) Nomenclature and characterization of leukocyte differentiation antigens in ruminants.
Immunol Today. 18 (8): 365-8. 4. Howard, C.J. & Naessens, J. (1993) Summary of workshop findings for cattle (tables 1 and 2).
Vet Immunol Immunopathol. 39 (1-3): 25-47. 5. Nguyen, T.K. et al. (2013) The bovine CD1D gene has an unusual gene structure and is expressed but cannot present a-galactosylceramide with a C26 fatty acid.
Int Immunol. 25: 91-8. 6. Van Rhijn, I. et al. (2006) The bovine CD1 family contains group 1 CD1 proteins, but no functional CD1d.
J Immunol. 176: 4888-93. 7. Rhind, S.M. et al. (1996) Discrimination of two subsets of CD1 molecules in the sheep.
Vet Immunol Immunopathol. 52: 265-70. 8. Gibson, A. et al. (2012) Identification of a lineage negative cell population in bovine peripheral blood with the ability to mount a strong type I interferon response.
Dev Comp Immunol. 36: 332-41. 9. Goldfinch, N. et al. (2010) Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen.
Vet Res. 41: 62. 10. Gunnes, G. et al. (2000) Accessory cell populations in draining lymph nodes of lambs in the elicitation phase of DNCB-induced contact hypersensitivity.
Vet Immunol Immunopathol. 76: 75-88. 11. Jörundsson, E. (2000) Distribution of MHC-II and CD1 molecules in the skin of lambs and changes during experimentally-induced contact hypersensitivity.
Vet Immunol Immunopathol. 74: 87-101.

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