|Application ||FC, IP|
|Calculated MW||88369 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Other Names||Dipeptidyl peptidase 4, 22.214.171.124, Activation molecule 3, ACT3, Adenosine deaminase complexing protein, ADCP-I, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, WC10, CD26, Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV soluble form, DPP4, CD26|
|Target/Specificity||Mouse anti-Bovine CD26 antibody, clone CC69 recognizes bovine Dipeptidyl peptidase 4, also known as CD26, WC10, Adenosine deaminase complexing protein or Activation molecule 3 (Leeet al.2001). Bovine CD26 is a 765 amino acid single pass type II transmembrane glycoprotein which can be cleaved between residues 37-38 to release a soluble form of the protein. CD26 can exist as a monomer, forms a homodimer for optimal dipeptidase activity or it can form a heterodimer with seprase(UniProt: P81425). CD26 is expressed by a subpopulation of CD2+ T cells, dendritic cells and weakly by most B cells and is also seen on some non-haematopoietic cells, especially gut epithelium. Myeloid cells and the majority of WC1+ve T cells do not express CD26.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Bovine CD26 Antibody, clone CC69 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Howard, C.J. & Naessens, J. (1993) Summary of workshop findings for cattle (tables 1 and 2).Vet Immunol Immunopathol. 39 (1-3): 25-47. 2. Naessens, J. et al. (1993) Cross-reactivity of workshop antibodies with cells from domestic and wild ruminants.Vet Immunol Immunopathol. 39 (1-3): 283-90. 3. Epardaud, M. et al. (2004) Enrichment for a CD26hi SIRP- subset in lymph dendritic cells from the upper aero-digestive tract.J Leukoc Biol. 76: 553-61. 4. Contreras, V. et al. (2010) Existence of CD8a-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species.J Immunol. 185: 3313-25. 5. Fries, P.N. et al. (2011) Age-related changes in the distribution and frequency of myeloid and T cell populations in the small intestine of calves.Cell Immunol. 271: 428-37. 6. Ferret-Bernard, S. et al. (2010) Cellular and molecular mechanisms underlying the strong neonatal IL-12 response of lamb mesenteric lymph node cells to R-848.PLoS One. 5: e13705.
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