|Application ||IHC-F, FC|
|Calculated MW||82379 Da|
|Immunogen||Porcine CD31/human IgGFc fusion protein.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Platelet endothelial cell adhesion molecule, PECAM-1, CD31, PECAM1|
|Target/Specificity||Mouse anti-Pig CD31 antibody, clone LCI-9 recognises porcine Platelet endothelial cell adhesion molecule, also known as CD31 or PECAM-1. Porcine CD31 is a 740 amino acid ~140kDa single pass type 1 transmembrane glycoprotein bearing six Ig-like C2-type domains. CD31 is expressed by various cell types, but particularly by endothelial cells where it is required for leukocyte transendothelial migration (UniProt:Q95242).Mouse anti-Pig CD31 antibody, clone LCI-9 has been used successfully for recognition of porcine CD31 by flow cytometry (Petersonet al.2005) and immunofluorescence microscopy (Nasuet al.1999).|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Pig CD31 Antibody, clone LCI-9 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Peterson, M.D. et al. (2005) Monocyte adhesion to xenogeneic endothelium during laminar flow is dependent on alpha-Gal-mediated monocyte activation.J. Immunol. 174: 8072- 81 2. Nasu, K. et al. (1999) Alpha-galactosyl-mediated activation of porcine endothelial cells: studies on CD31 and VE-cadherin in adhesion and signaling.Transplantation. 1999 Sep 27;68(6): 861-7. 3. Peterson, M.D. et al. (2005) Monocyte-induced endothelial calcium signaling mediates early xenogeneic endothelial activation.Am J Transplant. 5: 237-47. 4. Harrower, T.P. et al. (2006) Long-term survival and integration of porcine expanded neural precursor cell grafts in a rat model of Parkinson's disease.Exp Neurol. 197: 56-69. 5. Al-Shalmani, S. et al. (2011) Quercetin and its principal metabolites, but not myricetin, oppose lipopolysaccharide-induced hyporesponsiveness of the porcine isolated coronary artery.Br J Pharmacol. 162: 1485-97.5. Piriou-Guzylack, L. (2008) Membrane markers of the immune cells in swine: an update.Vet Res. 39: 54.
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