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Anti-hCG (Beta 1 Epitope) Antibody, clone INN-hCG-2

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01233
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names INN-hCG-2
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen hCG.
Shelf Life 18 months from date of despatch.
Other Names Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta, CGB, CGB3
Target/Specificity Mouse anti-hCG antibody, clone INN-hCG-2 recognizes the beta 1 epitope on human chorionic gonadotrophin (hCG).Chorionic gonadotrophin is a member of the glycoprotein hormone family that is synthesized by the placenta throughout pregnancy. The glycoprotein hormone family has 4 members, the other three being luteinising hormone (LH), follicle stimulating hormone (FSH) and thyroid stimulating hormone (TSH). All consist of two subunits, alpha and beta. The alpha subunit is highly homologous between family members.Mouse anti-hCG antibody, clone INN-hCG-2 is reactive with hCG, hCGbeta, hCGbetacf (fragment), hCGn (nicked), hCGbetan, and CTP-hCG. No cross reaction is observed with hLH, hLHbeta, hFSH, hTSH, or the glycoprotein hormone alpha chains.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-hCG (Beta 1 Epitope) Antibody, clone INN-hCG-2 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Kofler, R. et al. (1982) Monoclonal antibodies against human chorionic gonadotropin (hCG): I. Production, specificity, and intramolecular binding sites.
Am. J. Reprod. Immunol. 2: 212-216. 2. Berger, P. et al. (1993) Variants of human chorionic gonadotropin from pregnant women and tumor patients recognized by monoclonal antibodies.
J. Clin. Endocrinol. Metab. 77: 347-351. 3. Zimmermann, G. et al. (2009) Zimmermann G, Ackermann W, Alexander H. Epithelial human chorionicEpithelial human chorionic gonadotropin is expressed and produced in human secretory endometrium during the normal menstrual cycle. Biol Reprod. 2009 May;80(5):1053-65. Epub 2009 Jan 21.PubMed PMID: 19164178.
Biol Reprod. 80:1053-65. 4. Zimmermann, G. et al. (2003) Expression of beta hCG and alpha CG mRNA and hCG hormone in human decidual tissue in patients during tubal pregnancy.
Mol Hum Reprod. 9: 81-9. 5. Charrel-Dennis, M. et al. (2005) The human chorionic gonadotropin-beta arginine68 to glutamic acid substitution fixes the conformation of the C-terminal peptide.
Mol Endocrinol. 19: 1803-11.

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Cat# ABD11657
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