|Application ||WB, E, Func|
|Clone Names||CA 102.2C1|
|Calculated MW||40155 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Bacterially expressed human MAdCAM-1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Mucosal addressin cell adhesion molecule 1, MAdCAM-1, hMAdCAM-1, MADCAM1|
|Target/Specificity||Mouse anti-Human MAdCAM-1 antibody, clone CA102.2C1 recognizes human mucosal addressin cell adhesion molecule -1, also known as MAdCAM-1. Human MAdCAM-1 is a 382 amino acid ~40-60 kDa single pass type 1 transmembrane glycoprotein expressed by vascular endothelium (http://www.uniprot.org/uniprot/Q13477).Mouse anti-Human MAdCAM-1 antibody, clone CA102.2C1 has been reported to block the binding of human cells expressing alpha4 Beta7 to immobilized MAdCAM-1 in vitro(Grantet al.2001).|
|Preservative & Stabilisers||Preservative Free|
|Storage||Store at -20℃ only.|
|Precautions||Anti-Human MAdCAM-1 Antibody, clone CA 102.2C1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Eksteen, B. et al. (2006) Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10.J Immunol. 177: 593-603. 2. Liaskou, E. et al. (2011) Regulation of mucosal addressin cell adhesion molecule 1 expression in human and mice by vascular adhesion protein 1 amine oxidase activity.Hepatology. 53: 661-72.
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