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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Aquaporin 1 Antibody, clone 1/A5F6    

Anti-Aquaporin 1 Antibody, clone 1/A5F6

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P29972
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 1/A5F6
Calculated MW 28526 Da
Additional Information
Other Species M,Rat,Rb,Zf
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Synthetic peptide corresponding to amino acids 249-269 of aquaporin 1.
Shelf Life 18 months from date of despatch.
Gene ID 358
Other Names Aquaporin-1, AQP-1, Aquaporin-CHIP, Urine water channel, Water channel protein for red blood cells and kidney proximal tubule, AQP1, CHIP28
Target/Specificity Clone 1/A5F6 recognizes an epitope within the cytoplasmic domain of the water-specific channel aquaporin 1 (also known as AQP1 or CHIP-28).Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and the kidney. AQP1 is also expressed by the choroid plexus and various other tissues. The glycosylated forms of AQP1 range between 40-60kD in mass.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Aquaporin 1 Antibody, clone 1/A5F6 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Nagy, G. et al. (2002) Development and characterisation of a monoclonal antibody family againstaquaporin 1 (AQP1) and aquaporin 4 (AQP4).
Pathol. Oncol. Res. 8: 115-124. 2. Bodis, B. et al. (2001) Active water selective channels in the stomach: investigation of aquaporins after ethanol and capsaicin treatment in rats.
J. Physiol. 95: 271-275. 3. Francone, V.P. et al (2010) Signaling from the secretory granule to the nucleus: Uhmk1 and PAM.
Mol Endocrinol. 24: 1543-58. 4. Felszeghy, S. et al (2004) Expression of aquaporin isoforms during human and mouse tooth development.
Arch Oral Biol. 49: 247-57. 5. Ripoche, P. et al. (2004) Human Rhesus-associated glycoprotein mediates facilitated transport of NH(3) into red blood cells.
Proc Natl Acad Sci U S A. 101: 17222-7. 6. Lupp, A. et al. (2010) Immunohistochemical identification of the PTHR1 parathyroid hormone receptor in normal and neoplastic human tissues.
Eur J Endocrinol. 162: 979-86. 7. Pannabecker, T.L. et al. (2008) Quantitative analysis of functional reconstructions reveals lateral and axial zonation in the renal inner medulla.
Am J Physiol Renal Physiol. 294: F1306-14. 8. Thiele, S. et al. (2007) A disruptive mutation in exon 3 of the GNAS gene with albright hereditary osteodystrophy, normocalcemic pseudohypoparathyroidism, and selective long transcript variant Gsalpha-L deficiency.
J Clin Endocrinol Metab. 92: 1764-8. 9. Antonelou, M.H. et al. (2011) Oxidative stress-associated shape transformation and membrane proteome remodeling in erythrocytes of end stage renal disease patients on hemodialysis.
J Proteomics. 74: 2441-52. 10. Arnaud, L. et al. (2010) A functional AQP1 allele producing a Co(a-b-) phenotype revises and extends the Colton blood group system.
Transfusion. 50: 2106-16. 11. Saison, C. et al. (2012) A new AQP1 null allele identified in a Gypsy woman who developed an anti-CO3 during her first pregnancy.
Vox Sang. 103: 137-44.

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