|Application ||WB, IHC-F|
|Calculated MW||38298 Da|
|Shelf Life||18 months from date of despatch.|
|Other Names||Beta-2-glycoprotein 1, APC inhibitor, Activated protein C-binding protein, Anticardiolipin cofactor, Apolipoprotein H, Apo-H, Beta-2-glycoprotein I, B2GPI, Beta(2)GPI, APOH, B2G1|
|Target/Specificity||Mouse anti-Human apolipoprotein H antibody, clone 1D2 recognises the human Apolipoprotein H molecule, also known as beta 2 glycoprotein 1, APC inhibitor, activated protein C-binding protein or anticardiolipin cofactor. Apolipoprotein H is expressed by placental trophoblast cells at high levels. Although the normal physiological role is not known, the protein appears to act as a co-factor for the binding of autoantibodies to phospholipids to trophoblasts, a process involved in the pathogenesis of recurrent miscarriage and thrombotic tendencies due to antiphospholipid syndrome.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Apolipoprotein H Antibody, clone ID2 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Mak, I.Y. et al. (2002) Regulated expression of signal transducer and activator of transcription, Stat5, and its enhancement of PRL expression in human endometrial stromal cells in vitro.J. Clin. Endocrinol. Metab. 87: 2581-8. 2. Vlachoyiannopoulos, P.G. et al. (2004) Anti-CD40 antibodies in antiphospholipid syndrome and systemic lupus erythematosus.Thromb Haemost. 92: 1303-11. 3. Goonetilleke, U.R. et al. (2012) Death Is Associated with Complement C3 Depletion in Cerebrospinal Fluid of Patients with Pneumococcal Meningitis mBio 3: e00272-11 1. Chamley, L. W. et al. (2001) Is interleukin-3 important in antiphospholipid antibody-mediated pregnancy failure? Fertil. Steril. 76: 700 - 706.
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