|Calculated MW||27716 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||Purified human Granzyme B.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Granzyme B, 18.104.22.168, C11, CTLA-1, Cathepsin G-like 1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, HLP, SECT, T-cell serine protease 1-3E, GZMB, CGL1, CSPB, CTLA1, GRB|
|Target/Specificity||Mouse anti-Human granzyme B antibody, clone GB10 recognizes the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs).Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death.|
|Preservative & Stabilisers||0.09% Sodium Azide; 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Granzyme B Antibody, clone GB10 (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Spaeny-Dekking, E. H. A. et al. (1998) Extracellular Granzymes A and B in humans: Detection of native species during CTL responses in vitroandin vivo.J. Immunol. 160: 3610 - 3616.
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